Temporary Senior Scientist, Upstream Process Development

Our purpose is to bring hope to life by enabling life-changing therapies for patients around the globe, creating a healthier and happier tomorrow. Our mission is to work side by side with our customers in order to improve patients’ lives by bringing new biopharmaceuticals to market. Would you like to participate in scientific innovation that makes a difference in patients’ lives? And do you have cell culture experience? Then join AGC Biologics as a Scientist/Senior Scientist (12 months maternity cover) in Upstream Process Development and become part of an international and modern organization that delivers biopharmaceutical development and manufacturing. We get it right. On time. The Department The Upstream Process Development group is responsible for cell line development, cell culture process development, fermentation process development, process characterization and upstream process and technology transfers. Projects range from early pre-clinical development through all phases of clinical development all the way to commercial supply. Upstream Development is also responsible for all cGMP cell banking activities, design of platform processes and evaluation and implementation of new upstream technologies and techniques. The work environment in our department is very informal. There is constant collaboration across the entire organization, and all employees have a very professional and flexible attitude towards their work. Responsibilities and tasks As a Scientist/Senior Scientist, you will be involved in multiple upstream development projects, and participate in multi-disciplinary project teams including upstream, downstream and analytical scientists working in close collaboration with the clients’ scientific teams. The upstream process development team is covering both microbial and mammalian cell culture projects. For this position we are mainly looking for a mammalian cell culture expert and you will be involved in cell culture process development, cell culture optimizations, process characterization and manufacturing support. The process development in bioreactors is performed in scales from 250 mL up to 200L. Development, evaluation and scale up of new process methodologies in the development laboratory are also some of the responsibilities of the team. The job includes:

• planning and coordination of activities and experiments
• verbal and written reporting to clients
• strategic technology development
• technical guidance within development and manufacturing
• technical advice to business development

Experience and competencies Ideally, you hold a PhD in Cell Biology, Biochemistry or Biochemical Engineering. In addition, you have:

• relevant experience from the industry
• demonstrated expertise within developing upstream processes – preferably within perfusion technology
• thorough understanding of how modifications in cell culture conditions affect the quality and functional activity of proteins
• experience in handling bioreactors; fed-batch and/or perfusion
• experience on late stage process optimization/process characterization is desirable
• good interpersonal and communication skills
• ability to handle several projects simultaneously
• experience in planning, performing and reporting experiments
• fluency in English, written and spoken

For further information regarding the position please contact Caroline Mathiesen, Manager in Upstream Process Development, cbkmathiesen@agcbio.com. We will process the applications as they arrive. Therefore, please submit your application and CV as soon as possible and no later than June 15th 2024. Our culture at AGC Biologics is defined by the six core values: Knowledge, Trust, Quality, Ingenuity, Accountability and Teamwork. Our core values stem from our team members and are embedded into our DNA. They provide a common language and understanding of how we as an organization are connected across three continents. Our core values serve as a compass and reminder of how we achieve our purpose of bringing hope to life for patients around the globe.
AGC Biologics is a leading global biopharmaceutical Contract Development and Manufacturing Organization (CDMO) with a strong commitment to delivering the highest standard of service as we work side-by-side with our clients and partners, every step of the way. We provide world-class development and manufacture of mammalian and microbial-based therapeutic proteins, plasmid DNA (pDNA), messenger RNA (mRNA), viral vectors, and genetically engineered cells. Our global network spans the U.S., Europe, and Asia, with cGMP-compliant facilities in Seattle, Washington; Boulder and Longmont, Colorado; Copenhagen, Denmark; Heidelberg, Germany; Milan, Italy; and Chiba, Japan. We currently employ more than 2,500 employees worldwide. Our commitment to continuous innovation fosters the technical creativity to solve our clients’ most complex challenges, including specialization in fast-track projects and rare diseases. AGC Biologics is the partner of choice. To learn more, visit www.agcbio.com. Want to keep posted about our growth and learn more about our company? Follow us on LinkedIn and give us a quick Like on Facebook ! AGC Biologics offers a highly competitive compensation package and a friendly, collaborative culture that values personal initiative and professional achievement. AGC Biologics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, color, family or medical care leave, gender identity or expression, genetic information, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran status, race, religion, sexual orientation, or any other characteristic protected by applicable laws, regulations and ordinances.